Answers to know for job interviews

Lifehacker included these two answers in their summary. More available from 10 Answers You Should Know Before Your Job Interview [Dumb Little Man]

Tell me about yourself.
Chances are the employer doesn't want to know how much you weighed when you were born, when you learned to tie your shoes, or how much you had to drink last night. He or she wants to know how you would fit into the company and what your relevant job experience is. You might answer by asking the interviewer what he'd like to know. Or you might talk about your education, the fact that you're a team player, or whatever you think might be important to this particular company.

Why did you leave your last job?
Never put your former employer or your co-workers in a negative light. Don't blame them for your departure. Give a positive reason, such as you left to take advantage of another opportunity that was better suited to your skills.

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Do you have questions for me?
Always have a few questions. They show that you researched the company. Ask about a
current issue the company is working on or how their recent layoff in another department
affected company morale.